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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
07/10/2019 |
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Actualizado : |
07/10/2019 |
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Tipo de producción científica : |
Documentos |
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Autor : |
INIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA); HORACK, A.; GARCÍA, M. J. (Ed.). |
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Afiliación : |
ALEJANDRO HORACK REY, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARÍA JOSÉ GARCÍA LENA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
INIA Informa (No.4, Agosto-Setiembre 2019). |
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Fecha de publicación : |
2019 |
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Fuente / Imprenta : |
Montevideo (UY): INIA, 2019 |
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Páginas : |
15 p. |
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Idioma : |
Español |
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Contenido : |
CONTENIDO.
1.- La Dirección Nacional de INIA se muda a fines de 2019 al Parque Tecnológico del LATU.
2.- El acuerdo con la Unión Europea nos pone bajo la lupa de los países que nos compran carne. Ing. Agr. (PhD) Marcia del Campo, investigadora principal del Programa de Carne y Lana de INIA.
3.- INIA rinde cuentas de su labor mediante la medición de indicadores clave de desempeño. Ing. Agr. (PhD) Fabio Montossi, Director Nacional de INIA.
4.- INIA investiga herramientas para que los cítricos lleguen en buenas condiciones a los mercados de exportación. Ing. Agr. (PhD) Joanna Lado, investigadora principal de Calidad y Postcosecha en INIA Salto Grande del Programa Nacional de Citricultura.
5.- Tener sistemas de producción ovina sostenibles y biodiversos sería positivo para todos. Ing. Agr. (PhD) Ignacio de Barbieri, investigador del Programa de Carne y Lana de INIA.
6.- Qué es y qué implica el mejoramiento genético? INIA respondió a esta pregunta en Expo Prado 2019. |
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Palabras claves : |
BOLETÍN INFORMATIVO. |
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Thesagro : |
DIFUSIÓN; INVESTIGACIÓN. |
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Asunto categoría : |
-- |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/13435/1/INIA-Informa-n.-4.pdf
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Marc : |
LEADER 01504nam a2200181 a 4500
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008 2019 bl uuuu u0uu1 u #d
100 1 $aINIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA)
245 $aINIA Informa (No.4, Agosto-Setiembre 2019).$h[electronic resource]
260 $aMontevideo (UY): INIA$c2019
300 $a15 p.
520 $aCONTENIDO. 1.- La Dirección Nacional de INIA se muda a fines de 2019 al Parque Tecnológico del LATU. 2.- El acuerdo con la Unión Europea nos pone bajo la lupa de los países que nos compran carne. Ing. Agr. (PhD) Marcia del Campo, investigadora principal del Programa de Carne y Lana de INIA. 3.- INIA rinde cuentas de su labor mediante la medición de indicadores clave de desempeño. Ing. Agr. (PhD) Fabio Montossi, Director Nacional de INIA. 4.- INIA investiga herramientas para que los cítricos lleguen en buenas condiciones a los mercados de exportación. Ing. Agr. (PhD) Joanna Lado, investigadora principal de Calidad y Postcosecha en INIA Salto Grande del Programa Nacional de Citricultura. 5.- Tener sistemas de producción ovina sostenibles y biodiversos sería positivo para todos. Ing. Agr. (PhD) Ignacio de Barbieri, investigador del Programa de Carne y Lana de INIA. 6.- Qué es y qué implica el mejoramiento genético? INIA respondió a esta pregunta en Expo Prado 2019.
650 $aDIFUSIÓN
650 $aINVESTIGACIÓN
653 $aBOLETÍN INFORMATIVO
700 1 $aHORACK, A.
700 1 $aGARCÍA, M. J.
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Registro original : |
INIA Las Brujas (LB) |
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha actual : |
07/06/2019 |
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Actualizado : |
05/09/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
GIANNITTI, F.; CAFFARENA, D.; PESAVENTO, P.; UZAL, F.A.; MAYA, L.; FRAGA, M.; COLINA, R.; CASTELLS, M. |
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Afiliación : |
FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RUBEN DARÍO CAFFARENA LEDESMA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; PATRICIO PESAVENTO, Pathology, Microbiology and Immunology Department, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.; FRANCISCO ALEJANDRO UZAL, Pathology, Microbiology and Immunology Department, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.; LETICIA MAYA, Laboratorio de Virología Molecular, Centro Universitario Regional (CENUR) Litoral Norte, Universidad de la República, Salto, Uruguay.; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RODNEY COLINA, Laboratorio de Virología Molecular, Centro Universitario Regional (CENUR) Litoral Norte, Universidad de la República, Salto, Uruguay.; MATÍAS CASTELLS BAUER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.//Laboratorio de Virología Molecular, Centro Universitario Regional (CENUR) Litoral Norte, Universidad de la República, Salto, Uruguay. |
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Título : |
The first case of bovine astrovirus-associated encephalitis in the southern hemisphere (Uruguay), uncovers evidence of viral introduction to the Americas from Europe. |
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Fecha de publicación : |
2019 |
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Fuente / Imprenta : |
Frontiers in Microbiology, volumen 10, Article 1240, 04 June 2019. [OPEN ACCESS].Doi: https://doi.org/10.3389/fmicb.2019.01240 |
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DOI : |
10.3389/fmicb.2019.01240 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: 22 March 2019//Accepted: 17 May 2019//Published: 04 June 2019. This work was funded by Grants PL-015 N-15156 from INIA and 158 from the ?Programa de Iniciación a la Investigación 2017? from ?Comisión Sectorial de Investigación Científica? (CSIC). MC and RDC acknowledge support from the ?Agencia Nacional de Investigación e Innovación? (ANII) and INIA, respectively, through Ph.D. scholarships. FG acknowledges support from ANII through mobility grant MOV_CA_2018_1_150021. |
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Contenido : |
Abstract: Astrovirus species members of the Mamastrovirus genus (family Astroviridae) have been increasingly recognized as neuroinvasive pathogens in various mammals, including humans, mink, cattle, sheep, and pigs. While cases of astrovirus-associated encephalitis have been reported in North America, Europe, and Asia, their presence has never been documented in the Southern hemisphere. This paper describes a case of astrovirus-associated encephalitis in cattle in Uruguay that broadens the geographic distribution and genetic diversity of neuroinvasive astroviruses and provides phylogeographic evidence of viral introduction to the Americas from Europe. A 22-month-old Holstein steer from a farm in Colonia Department, Uruguay developed progressive neurological signs over a 3-days period before dying. Histopathological examination of the brain and proximal cervical spinal cord revealed disseminated, moderate to severe lymphocytic, histiocytic, and plasmacytic poliomeningoencephalomyelitis with neuronal necrosis. A Mamastrovirus strain in the CH13/NeuroS1 clade, that we called bovine astrovirus (BoAstV)-Neuro-Uy, was identified by reverse transcriptase PCR followed by nearly complete genome sequencing. Additionally, BoAstV was detected intralesionally in the brain by chromogenic RNA in situ hybridization within neuronal perikarya, axons and dendrites. Phylogenetic analysis of BoAstV-Neuro-Uy revealed a close relationship to neurotropic BoAstVs within the Virginia/Human-Mink-Ovine clade, which contains a growing cadre of neuroinvasive astroviruses. Analyzing the complete coding region of neuroinvasive BoAstVs sequences available in GenBank, we estimated an evolutionary rate of 4.27 × 10-4 (95% HPD 2.19?6.46 × 10-4) nucleotide substitutions/site/year. Phylogeographic analysis suggests that the common viral ancestor circulated in Europe between 1794?1940, and was introduced in Uruguay between 1849?1967, to later spread to North America and Japan. MenosAbstract: Astrovirus species members of the Mamastrovirus genus (family Astroviridae) have been increasingly recognized as neuroinvasive pathogens in various mammals, including humans, mink, cattle, sheep, and pigs. While cases of astrovirus-associated encephalitis have been reported in North America, Europe, and Asia, their presence has never been documented in the Southern hemisphere. This paper describes a case of astrovirus-associated encephalitis in cattle in Uruguay that broadens the geographic distribution and genetic diversity of neuroinvasive astroviruses and provides phylogeographic evidence of viral introduction to the Americas from Europe. A 22-month-old Holstein steer from a farm in Colonia Department, Uruguay developed progressive neurological signs over a 3-days period before dying. Histopathological examination of the brain and proximal cervical spinal cord revealed disseminated, moderate to severe lymphocytic, histiocytic, and plasmacytic poliomeningoencephalomyelitis with neuronal necrosis. A Mamastrovirus strain in the CH13/NeuroS1 clade, that we called bovine astrovirus (BoAstV)-Neuro-Uy, was identified by reverse transcriptase PCR followed by nearly complete genome sequencing. Additionally, BoAstV was detected intralesionally in the brain by chromogenic RNA in situ hybridization within neuronal perikarya, axons and dendrites. Phylogenetic analysis of BoAstV-Neuro-Uy revealed a close relationship to neurotropic BoAstVs within the Virginia/Human-Mink-Ovine... Presentar Todo |
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Palabras claves : |
BOVINE ASTROVIRUS; CATTLE; ENCEPHALITIS; ENFERMEDADES INFECCIOSAS; INFECTIOUS DISEASE; MAMASTROVIRUS; PHYLOGEOGRAPHY; PLATAFORMA SALUD ANIMAL. |
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Thesagro : |
SUD AMERICA; URUGUAY. |
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Asunto categoría : |
E16 Enfermedades de los animales |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16714/1/fmicb-10-01240.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559012/pdf/fmicb-10-01240.pdf
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Marc : |
LEADER 03592naa a2200349 a 4500
001 1059833
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008 2019 bl uuuu u00u1 u #d
024 7 $a10.3389/fmicb.2019.01240$2DOI
100 1 $aGIANNITTI, F.
245 $aThe first case of bovine astrovirus-associated encephalitis in the southern hemisphere (Uruguay), uncovers evidence of viral introduction to the Americas from Europe.$h[electronic resource]
260 $c2019
500 $aArticle history: Received: 22 March 2019//Accepted: 17 May 2019//Published: 04 June 2019. This work was funded by Grants PL-015 N-15156 from INIA and 158 from the ?Programa de Iniciación a la Investigación 2017? from ?Comisión Sectorial de Investigación Científica? (CSIC). MC and RDC acknowledge support from the ?Agencia Nacional de Investigación e Innovación? (ANII) and INIA, respectively, through Ph.D. scholarships. FG acknowledges support from ANII through mobility grant MOV_CA_2018_1_150021.
520 $aAbstract: Astrovirus species members of the Mamastrovirus genus (family Astroviridae) have been increasingly recognized as neuroinvasive pathogens in various mammals, including humans, mink, cattle, sheep, and pigs. While cases of astrovirus-associated encephalitis have been reported in North America, Europe, and Asia, their presence has never been documented in the Southern hemisphere. This paper describes a case of astrovirus-associated encephalitis in cattle in Uruguay that broadens the geographic distribution and genetic diversity of neuroinvasive astroviruses and provides phylogeographic evidence of viral introduction to the Americas from Europe. A 22-month-old Holstein steer from a farm in Colonia Department, Uruguay developed progressive neurological signs over a 3-days period before dying. Histopathological examination of the brain and proximal cervical spinal cord revealed disseminated, moderate to severe lymphocytic, histiocytic, and plasmacytic poliomeningoencephalomyelitis with neuronal necrosis. A Mamastrovirus strain in the CH13/NeuroS1 clade, that we called bovine astrovirus (BoAstV)-Neuro-Uy, was identified by reverse transcriptase PCR followed by nearly complete genome sequencing. Additionally, BoAstV was detected intralesionally in the brain by chromogenic RNA in situ hybridization within neuronal perikarya, axons and dendrites. Phylogenetic analysis of BoAstV-Neuro-Uy revealed a close relationship to neurotropic BoAstVs within the Virginia/Human-Mink-Ovine clade, which contains a growing cadre of neuroinvasive astroviruses. Analyzing the complete coding region of neuroinvasive BoAstVs sequences available in GenBank, we estimated an evolutionary rate of 4.27 × 10-4 (95% HPD 2.19?6.46 × 10-4) nucleotide substitutions/site/year. Phylogeographic analysis suggests that the common viral ancestor circulated in Europe between 1794?1940, and was introduced in Uruguay between 1849?1967, to later spread to North America and Japan.
650 $aSUD AMERICA
650 $aURUGUAY
653 $aBOVINE ASTROVIRUS
653 $aCATTLE
653 $aENCEPHALITIS
653 $aENFERMEDADES INFECCIOSAS
653 $aINFECTIOUS DISEASE
653 $aMAMASTROVIRUS
653 $aPHYLOGEOGRAPHY
653 $aPLATAFORMA SALUD ANIMAL
700 1 $aCAFFARENA, D.
700 1 $aPESAVENTO, P.
700 1 $aUZAL, F.A.
700 1 $aMAYA, L.
700 1 $aFRAGA, M.
700 1 $aCOLINA, R.
700 1 $aCASTELLS, M.
773 $tFrontiers in Microbiology, volumen 10, Article 1240, 04 June 2019. [OPEN ACCESS].Doi: https://doi.org/10.3389/fmicb.2019.01240
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